AZ9482

Item number	Size	Manual	SDS	Delivery time	Price
SYN-3046-M001	1 mg	-	-	3 - 9 business days*	119.00€
SYN-3046-M005	5 mg	-	-	3 - 9 business days*	250.00€
SYN-3046-M010	10 mg	-	-	3 - 9 business days*	382.00€
SYN-3046-M050	50 mg	-	-	3 - 9 business days*	1,172.00€
SYN-3046-M100	100 mg	-	-	3 - 9 business days*	-

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AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a... more

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Product information "AZ9482"

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also showed a 3nM GI50 in the DLBCL cell line OCI-LY-19 in a 3-day AlamarBlue assay. Consistent with published siRNA knockdown experiments, AZ9482 was a 9nM enzyme inhibitor of tankyrase 1 (TNKS1).

Keywords:	2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile
Supplier:	SYNkinase
Supplier-Nr:	3046

Properties

Application:	Potent, selective PARP inhibitor
MW:	450.5 D
Formula:	C26H22N6O2
Purity:	>95%
Format:	Solid

Database Information

CAS :	1825345-33-2\| Matching products
KEGG ID :	K10798 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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