Autogramin-2
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Autogramin-2 is an inhibitor of Aster-A (IC50 = 1. µM), a protein that transports cholesterol... more
Product information "Autogramin-2"
Autogramin-2 is an inhibitor of Aster-A (IC50 = 1. µM), a protein that transports cholesterol from the plasma membrane to the endoplasmic reticulum (ER). Autogramin-2 is selective for Aster-A over Aster-B and -C (IC50s = >20 µM for both). It inhibits autophagy induced by amino acid starvation or rapamycin-mediated mammalian target of rapamycin 1 (mTORC1) inhibition in MCF-7 cells (IC50s = 0. and 0. µM, respectively). InChI: InChI=1S/C21H27N3O4S/c1-13(2)27-15-8-6-14(7-9-15)18(25)23-19-22-16-10-11-24(12-17(16)29-19)20(26)28-21(3,4)5/h6-9,13H,10-12H2,1-5H3,(H,22,23,25) InChIKey: PNSFNXURLSDVRV-UHFFFAOYSA-N SMILES: CC(OC1=CC=C(C(NC2=NC(CCN(C(OC(C)(C)C)=O)C3)=C3S2)=O)C=C1)C
| Keywords: | 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 1,1-dimethylethyl ester |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43556 |
Properties
| Application: | Aster-A (GRAMD1A) inhibitor |
| MW: | 417.52 D |
| Formula: | C21H27N3O4S |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 2375541-45-8| Matching products |
| KEGG ID : | K27898 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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