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Autogramin-2
Item number: Cay43556-10
Autogramin-2 is an inhibitor of Aster-A (IC50 = 1. µM), a protein that transports cholesterol from the plasma membrane to the endoplasmic reticulum (ER). Autogramin-2 is selective for Aster-A over Aster-B and -C (IC50s = >20 µM for both). It inhibits autophagy induced by amino acid starvation or rapamycin-mediated...
| Keywords: | 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 1,1-dimethylethyl ester |
| Application: | Aster-A (GRAMD1A) inhibitor |
| CAS | 2375541-45-8 |
| MW: | 417.52 D |
From 85.00€
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Autogramin-2
Item number: TGM-T9013-100mg
Description: Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 µM, and inhibits mTORC1 (Rapamycin, IC50:0.14 µM). Target: Autophagy. Smiles:...
| Keywords: | tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate |
| CAS | 2375541-45-8 |
| MW: | 417.52 D |
From 37.00€
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