(±)-Atenolol-d7

(±)-Atenolol-d7 is intended for use as an internal standard for the quantification of (±)-atenolol (Cay-17250) by GC- or LC-MS. (±)-Atenolol is an antagonist of the beta1-adrenergic receptor (beta1-AR, Ki = 1.14 µM). It is selective for beta1-ARs over beta2-ARs (Ki = 48.7 µM). (±)-Atenolol (200 mg/kg per day) delays the onset of hypertension in spontaneously hypertensive rats. Formulations containing atenolol have been used in the treatment of high blood pressure.Formal Name: 4-[2-hydroxy-3-[[1-(methyl-d3)ethyl-1,2,2,2-d4]amino]propoxy]-benzeneacetamide. CAS Number: 1202864-50-3. Synonyms: (R,S)-Atenolol-d7, Duraatenol, ICI 66082. Molecular Formula: C14D7H15N2O3. Formula Weight: 273.4. Purity: >99% deuterated forms (d1-d7). Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. SMILES: NC(CC1=CC=C(OCC(O)CNC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C=C1)=O. InChi Code: InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)/i1D3,2D3,10D. InChi Key: METKIMKYRPQLGS-SVMCCORHSA-N.