ART812

Item number	Size	Delivery time	Price
TGM-T40236-1mg	1 mg	7 - 10 business days*	111.00€
TGM-T40236-1mL	1 ml	7 - 10 business days*	278.00€
TGM-T40236-5mg	5 mg	7 - 10 business days*	280.00€
TGM-T40236-10mg	10 mg	7 - 10 business days*	448.00€
TGM-T40236-25mg	25 mg	7 - 10 business days*	743.00€
TGM-T40236-50mg	50 mg	7 - 10 business days*	1,099.00€
TGM-T40236-100mg	100 mg	7 - 10 business days*	1,535.00€

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Description: ART812 is an orally active inhibitor of DNA polymerase Poltheta, possessing an IC50... more

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Product information "ART812"

Description: ART812 is an orally active inhibitor of DNA polymerase Poltheta, possessing an IC50 value of 7.6 nM. Additionally, ART812 exhibits a cell-based microhomology-mediated end joining (MMEJ) IC50 value of 240 nM. Target: DNA/RNA Synthesis. Smiles: CN(C(=O)[C@@H]1[C@H](O)[C@H](O)C(=O)N1c1cc(cc(C)n1)C(F)(F)F)c1ccc(F)c(Cl)c1. References: Zatreanu D, et al. Poltheta inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021 Jun 17,12(1):3636.

Keywords:	ART812
Supplier:	TargetMol
Supplier-Nr:	T40236

Properties

MW:	461.79 D
Formula:	C19H16ClF4N3O4

Database Information

CAS :

2607138-82-7| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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