ARP 101

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Item number	Size	Manual	Delivery time	Price
Cay36212-1	1 mg	-	5 - 10 business days*	90.00€
Cay36212-5	5 mg	-	5 - 10 business days*	334.00€
Cay36212-10	10 mg	-	5 - 10 business days*	623.00€
Cay36212-25	25 mg	-	5 - 10 business days*	1,333.00€

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ARP 101 is an inhibitor of matrix metalloproteinase-2 (MMP-2, IC50 = 0.09 nM). It is selective... more

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Product information "ARP 101"

ARP 101 is an inhibitor of matrix metalloproteinase-2 (MMP-2, IC50 = 0.09 nM). It is selective for MMP-2 over MMP-1, -3, -7, -8, -9, and -14 (IC50s = 147, 50, >1,000, 1.6, 6.7, and 9.8 nM, respectively). ARP 101 inhibits the migration and invasion of human umbilical vein endothelial cells (HUVECs) and induces autophagy in MCF-7 breast cancer, SH-SY5Y neuroblastoma, and HCT116 colorectal cancer cells. It increases small intestine necrosis induced by indomethacin (Cay-70270) in rats.. SMILES: ONC([C@@H](C(C)C)N(OC(C)C)S(=O)(C1=CC=C(C2=CC=CC=C2)C=C1)=O)=O. InChi Code: InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1. InChi Key: DGZZVIWCMGVHGV-LJQANCHMSA-N

Keywords:	(2R)-2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-butanamide
Supplier:	Cayman Chemical
Supplier-Nr:	36212

Properties

Application:	MMP-2 inhibitor
MW:	406.5 D
Formula:	C20H26N2O5S
Purity:	>98%
Format:	Solid

Database Information

CAS :	849773-63-3\| Matching products
KEGG ID :	K01398 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)
Signal Word:	Warning
GHS Hazard Pictograms:
H Phrases:	H302, H361, H413
P Phrases:	P201, P202, P264, P270, P273, P280, P301+310, P308+313, P330, P405, P501