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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay25990-1 | 1 mg | - |
6 - 10 business days* |
50.00€
|
|||
Cay25990-5 | 5 mg | - |
6 - 10 business days* |
216.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
APC 366 is a mast cell tryptase inhibitor (Ki = 7.1 µM for human recombinant enzyme). It reduces... more
Product information "APC 366 (trifluoroacetate salt)"
APC 366 is a mast cell tryptase inhibitor (Ki = 7.1 µM for human recombinant enzyme). It reduces maximum contractile response to histamine in isolated bronchial tissue from ovalbumin-sensitized guinea pigs when used at a concentration of 1 µM. Aerosolized APC 366 (5 mg in 1 ml of water) reduces airway resistance and increases dynamic lung compliance in A. suum antigen-challenged pigs. It also reduces collagen content and expression of protease-activated receptor 2 (PAR-2) and alpha-smooth muscle actin (alpha-SMA) in rat liver in a model of bile duct ligation-induced liver fibrosis.Formal Name: N2-[(1-hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-L-prolinamide, trifluoroacetate salt. Molecular Formula: C22H28N6O4 . XCF3COOH. Formula Weight: 440.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Ethanol:Water: 5 mg/ml (in 20% EtOH). SMILES: OC1=C(C(N[C@@H](CCCNC(N)=N)C(N2[C@H](C(N)=O)CCC2)=O)=O)C=CC3=CC=CC=C31.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C22H28N6O4.C2HF3O2/c23-19(30)17-8-4-12-28(17)21(32)16(7-3-11-26-22(24)25)27-20(31)15-10-9-13-5-1-2-6-14(13)18(15)29,3-2(4,5)1(6)7/h1-2,5-6,9-10,16-17,29H,3-4,7-8,11-12H2,(H2,23,30)(H,27,31)(H4,24,25,26),(H,6,7)/t16-,17-,/m0./s1. InChi Key: FFLIQFBAKJNSSS-QJHJCNPRSA-N.
Keywords: | N2-[(1-hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-L-prolinamide, trifluoroacetate salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 25990 |
Properties
Application: | Mast cell tryptase inhibitor |
MW: | 440.5 D |
Formula: | C22H28N6O4 . XCF3COOH |
Purity: | >95% |
Format: | Solid |
Database Information
KEGG ID : | K01340 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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