142 products were found matching "K01340"!

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.

Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease, Ki = 15 nM), tryptase (a mast cell protease, Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 µM). In a mouse model of allergic asthma, a dose of 300 mg/kg...

Protein function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. [The UniProt Consortium]

In 1X PBS, pH 7.4, with 0.09% sodium azide. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on...

APC 366 is a mast cell tryptase inhibitor (Ki = 7.1 µM for human recombinant enzyme). It reduces maximum contractile response to histamine in isolated bronchial tissue from ovalbumin-sensitized guinea pigs when used at a concentration of 1 µM. Aerosolized APC 366 (5 mg in 1 ml of water) reduces airway resistance and...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TPS. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TPS. Next,...

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 31-275aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 6xHis-Myc-tagged. Target Protein Sequence: IVGGQEAPRS KWPWQVSLRV HGPYWMHFCG GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA DIALLELEEP VNVSSHVHTV...

Protein function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. [The UniProt Consortium]

In 1X PBS, pH 7.4, with 0.09% sodium azide. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on...

Protein function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient...