AMG 511
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
An inhibitor of class I PI3Ks, selective for PI3K over 372 other protein kinases at 1 µM,... more
Product information "AMG 511"
An inhibitor of class I PI3Ks, selective for PI3K over 372 other protein kinases at 1 µM, inhibits Akt phosphorylation in U87MG cells (IC50 = 4 nM), reduces tumor growth in a U87MG mouse xenograft model at doses of 1, 3, and 10 mg/kg per day. Formulation: A solid. InChI: InChI=1S/C22H28FN9O3S/c1-13(31-5-7-32(8-6-31)36(4,33)34)15-9-17(20-27-14(2)28-22(24)30-20)19(25-11-15)29-16-10-18(23)21(35-3)26-12-16/h9-13H,5-8H2,1-4H3,(H,25,29)(H2,24,27,28,30)/t13-/m1/s1. InChIKey: KUGIFHQBIIHRIZ-CYBMUJFWSA-N. SMILES: CC1=NC(C2=C(NC3=CN=C(C(F)=C3)OC)N=CC([C@@H](C)N4CCN(CC4)S(=O)(C)=O)=C2)=NC(N)=N1
| Keywords: | 4-[2-[(5-fluoro-6-methoxy-3-pyridinyl)amino]-5-[(1R)-1-[4-(methylsulfonyl)-1-piperazinyl]ethyl]-3-pyridinyl]-6-methyl-1,3,5-triazin-2-amine |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 41853 |
Properties
| Application: | Class I PI3K inhibitor |
| Immunogen: | 517.58 |
| MW: | 517.58 D |
| Formula: | C22H28FN9O3S |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1253573-53-3| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed