alphavbeta5 Integrin-IN-1

alphavbeta5 Integrin-IN-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39733-1 1 mg -

6 - 10 business days*

398.00€
 
alphavbeta5 Integrin-IN-1 is an inhibitor of alphaVbeta5 integrin (IC50 = 0.0063 µM). It is... more
Product information "alphavbeta5 Integrin-IN-1"
alphavbeta5 Integrin-IN-1 is an inhibitor of alphaVbeta5 integrin (IC50 = 0.0063 µM). It is selective for alphaVbeta5 over alphaVbeta1, alphaVbeta3, alphaVbeta6, and alphaVbeta8 (IC50s = 2.51, 5.01, 50.1, and 50.1 µM, respectively). alphavbeta5 Integrin-IN-1 inhibits adhesion of alphaVbeta5-expressing K562 cells to vitronectin-coated plates.Formal Name: (betaS,3R)-gamma-oxo-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-beta-[3-(trifluoromethyl)phenyl]-1-pyrrolidinebutanoic acid. CAS Number: 2615912-33-7. Synonyms: alphavbeta5 Integrin Inhibitor 1. Molecular Formula: C25H28F3N3O3. Formula Weight: 475.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Soluble. SMILES: O=C([C@@H](CC(O)=O)C1=CC(C(F)(F)F)=CC=C1)N2CC[C@@H](CCC(N3)=CC=C4C3=NCCC4)C2. InChi Code: InChI=1S/C25H28F3N3O3/c26-25(27,28)19-5-1-3-18(13-19)21(14-22(32)33)24(34)31-12-10-16(15-31)6-8-20-9-7-17-4-2-11-29-23(17)30-20/h1,3,5,7,9,13,16,21H,2,4,6,8,10-12,14-15H2,(H,29,30)(H,32,33)/t16-,21+/m1/s1. InChi Key: NUPIGKKRXBENIY-IERDGZPVSA-N.
Keywords: alphavbeta5 Integrin Inhibitor 1, (betaS,3R)-gamma-oxo-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-beta-[3-(trifluoromethyl)phenyl]-1-pyrrolidinebutanoic acid
Supplier: Cayman Chemical
Supplier-Nr: 39733

Properties

Application: AlphaVbeta5 integrin inhibitor
MW: 475.5 D
Formula: C25H28F3N3O3
Purity: >98%
Format: Solid

Database Information

CAS : 2615912-33-7| Matching products
KEGG ID : K06487 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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