AG490
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 µM). It is 135-fold more... more
Product information "AG490"
Description: AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 µM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src. Target: Autophagy, EGFR, JAK, STAT. Smiles: C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2. References: Gazit A, et al. J Med Chem, 1991, 34(6), 1896-1907.
| Keywords: | Zinc02557947, AG-490, Tyrphostin B42, Tyrphostin AG 490, AG 490 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2600 |
Properties
| Application: | JAK2 inhibitor |
| MW: | 294.3 D |
| Formula: | C17H14N2O3 |
Database Information
| CAS : | 133550-30-8| Matching products |
| KEGG ID : | K04447 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H400 |
| P Phrases: | P264, P270, P273, P301+310, P321, P330, P391, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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