Adavosertib

Item number	Size	Delivery time	Price
TGM-T2077-5mg	5 mg	7 - 10 business days*	42.00€
TGM-T2077-1mL	1 ml	7 - 10 business days*	45.00€
TGM-T2077-10mg	10 mg	7 - 10 business days*	63.00€
TGM-T2077-25mg	25 mg	7 - 10 business days*	77.00€
TGM-T2077-50mg	50 mg	7 - 10 business days*	93.00€
TGM-T2077-100mg	100 mg	7 - 10 business days*	117.00€
TGM-T2077-200mg	200 mg	7 - 10 business days*	172.00€
TGM-T2077-500mg	500 mg	7 - 10 business days*	287.00€

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Description: Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1... more

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Product information "Adavosertib"

Description: Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint. Target: Wee1. Smiles: C(C=C)N1N(C=2C(C1=O)=CN=C(NC3=CC=C(C=C3)N4CCN(C)CC4)N2)C=5N=C(C(C)(C)O)C=CC5. References: Hirai H, et al. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. Mol Cancer Ther. 2009 Nov,8(11):2992-3000.

Keywords:	MK-1775, AZD1775, Adavosertib (MK-1775)
Supplier:	TargetMol
Supplier-Nr:	T2077

Properties

Application:	Targets wee1-like protein kinase [EC:2.7.11.1] (WEE1)
MW:	500.6 D
Formula:	C27H32N8O2
Format:	32160405

Database Information

CAS :	955365-80-7\| Matching products
KEGG ID :	K06632 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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