Acetylthiocholine (iodide)

Acetylthiocholine is a substrate for acetylcholinesterase (AChE) and an agonist of alpha4beta2 subunit-containing nicotinic acetylcholine receptors (nAChRs). It binds to alpha4beta2 subunit-containing nAChRs in SH-EP1 cells (IC50 = 7.1 µM for the human receptor) and induces rubidium efflux in an agonist-induced rubidium efflux assay (EC50 = 100 µM). Acetylthiocholine has been used as part of a thiocholine sensor for the detection of pesticides in complex sample types, such as soil, groundwater, and spinach.Formal Name: 2-(acetylthio)-N,N,N-trimethyl-ethanaminium, monoiodide. CAS Number: 1866-15-5. Synonyms: ASCh, ATCh. Molecular Formula: C7H16NOS . I. Formula Weight: 289.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=C(C)SCC[N+](C)(C)C.[I-]. InChi Code: InChI=1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4,/h5-6H2,1-4H3,1H/q+1,/p-1. InChi Key: NTBLZMAMTZXLBP-UHFFFAOYSA-M.