Ac-IEPD-AFC

Item number	Size	Manual	SDS	Delivery time	Price
Cay42179-1	1 mg	-	-	6 - 10 business days*	42.00€
Cay42179-5	5 mg	-	-	6 - 10 business days*	177.00€
Cay42179-10	10 mg	-	-	6 - 10 business days*	312.00€
Cay42179-25	25 mg	-	-	6 - 10 business days*	727.00€

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A fluorogenic substrate for granzyme B, AFC is released upon enzymatic cleavage by granzyme B and... more

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Product information "Ac-IEPD-AFC"

A fluorogenic substrate for granzyme B, AFC is released upon enzymatic cleavage by granzyme B and its fluorescence can be used to quantify granzyme B activity, ex/em = 400/505 nm, respectively. Formulation: A solid. InChI: InChI=1S/C32H38F3N5O11/c1-4-15(2)27(36-16(3)41)30(49)38-20(9-10-24(42)43)31(50)40-11-5-6-22(40)29(48)39-21(14-25(44)45)28(47)37-17-7-8-18-19(32(33,34)35)13-26(46)51-23(18)12-17/h7-8,12-13,15,20-22,27H,4-6,9-11,14H2,1-3H3,(H,36,41)(H,37,47)(H,38,49)(H,39,48)(H,42,43)(H,44,45)/t15-,20-,21-,22-,27-/m0/s1. InChIKey: HWXKKVLJPWMVLL-FGGUPADCSA-N. SMILES: O=C([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@H](CC)C)=O)N1CCC[C@H]1C(N[C@H](C(NC2=CC=C3C(OC(C=C3C(F)(F)F)=O)=C2)=O)CC(O)=O)=O

Keywords:	Ac-Ile-Glu-Pro-Asp-AFC, (S)-4-((2S,3S)-2-acetamido-3-methylpentanamido)-5-((S)-2-(((S)-3-carboxy-1-oxo-1-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)amino)propan-2-yl)carbamoyl)pyrrolidin-1-yl)-5-oxopentanoic acid
Supplier:	Cayman Chemical
Supplier-Nr:	42179

Properties

Application:	Fluorogenic granzyme B substrate
Immunogen:	725.7
MW:	725.7 D
Formula:	C32H38F3N5O11
Purity:	>98%
Format:	Solid

Database Information

CAS :	1135417-31-0\| Matching products
KEGG ID :	K01353 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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