AC-264613

Item number	Size	Delivery time	Price
TGM-T4186-1mg	1 mg	7 - 10 business days*	125.00€
TGM-T4186-5mg	5 mg	7 - 10 business days*	397.00€
TGM-T4186-10mg	10 mg	7 - 10 business days*	730.00€
TGM-T4186-25mg	25 mg	7 - 10 business days*	1,659.00€

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Description: AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2).... more

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Product information "AC-264613"

Description: AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613(AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 30 to 100 nM. Target: Protease-activated Receptor. Smiles: CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1. References: Cosimi E, et al. Stereoselective Synthesis of alpha-Fluoro-gamma-nitro Thioesters under Organocatalytic Conditions. Org Lett. 2016 Dec 2,18(23):6014-6017

Keywords:	AC264613
Supplier:	TargetMol
Supplier-Nr:	T4186

Properties

Application:	PAR2 agonist
MW:	400.28 D
Formula:	C19H18BrN3O2

Database Information

CAS :	1051487-82-1\| Matching products
KEGG ID :	K04235 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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