No results were found for the filter!
FPR1 antagonist 1
Item number: TGM-T79781-50mg
Description: Compound 24a, an FPR1 antagonist, demonstrates potent inhibition of the formyl peptide receptor 1 (FPR1) with an IC50 value of 25 nM. It impedes cell proliferation and promotes apoptosis, thereby inhibiting cell growth. This compound also attenuates cell migration and concurrently promotes angiogenesis...
| MW: | 408.49 D |
Please request pricing for this article.
FPR1 antagonist 2
Item number: TGM-T79782-50mg
Description: Compound 25b, an FPR1 antagonist, exhibits potent inhibition of the formyl peptide receptor 1 with an IC50 of 70 nM. It concurrently hampers cell proliferation and triggers apoptosis, diminishing cell growth and migration, yet paradoxically augments angiogenesis [1]. Target: Others
| MW: | 462.46 D |
Please request pricing for this article.
NSC 48160
Item number: TGM-T79783-50mg
Description: NSC 48160, a chemical compound, exhibits inhibitory effects on pancreatic cancer cell proliferation, with half-maximal inhibitory concentrations (IC50s) of 84.3 µM for CPFAC-1 and 94.5 µM for BxPC-3. It also promotes apoptosis in pancreatic cancer cells. Additionally, NSC 48160 has been shown to...
| CAS | 6640-90-0 |
| MW: | 275.43 D |
From 177.00€
*
VU6004909
Item number: TGM-T79784-50mg
Description: VU6004909 is a positive allosteric modulator of the mGlu5 receptor (pEC50: 7.59), exhibiting antipsychotic-like effects. It has the capability to reverse MK801-induced cortical hyperactivity and cognitive deficits [1] [2]. Target: Others
| CAS | 1860797-76-7 |
| MW: | 378.35 D |
From 75.00€
*
Laxiflorin B
Item number: TGM-T79785-50mg
Description: Laxiflorin B, a novel selective inhibitor of ERK 1/2 derived from herbal sources, exhibits antitumor activity [1]. Target: ERK
| CAS | 165337-71-3 |
| MW: | 344.4 D |
Please request pricing for this article.
HPK1-IN-37
Item number: TGM-T79787-50mg
Description: HPK1-IN-37 (compound A85) is a potent HPK1 inhibitor with an IC50 value of 3.7 nM, suitable for research on HPK1-associated diseases and disorders, particularly cancers [1]. Target: Others
| CAS | 2766481-68-7 |
| MW: | 521.61 D |
Please request pricing for this article.
DT-6
Item number: TGM-T79789-50mg
Description: DT-6, a potent TGF-beta1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing potential for cancer research applications [1]. Target: TGF-beta/Smad
| CAS | 2414315-95-8 |
| MW: | 2008.23 D |
Please request pricing for this article.
ALPK1-IN-3
Item number: TGM-T79790-50mg
Description: ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced acute kidney injury [1]. Target: NF-kappaB
| CAS | 2765633-73-4 |
| MW: | 398.43 D |
Please request pricing for this article.
Immunosuppressant-1
Item number: TGM-T79791-50mg
Description: Immunosuppressant-1 (Compound 31) suppresses T-cell proliferation triggered by anti-CD3/anti-CD28 co-stimulation and demonstrates immunosuppressive effects, including the induction of apoptosis in activated lymph node cells through caspase-3 and PARP activation [1]. Target: Apoptosis
| CAS | 1224571-03-2 |
| MW: | 322.15 D |
Please request pricing for this article.
alphavbeta1 integrin-IN-2
Item number: TGM-T79792-50mg
Description: alphavbeta1 integrin-IN-2 (compound 32) is a potent inhibitor of alphanubeta1 and alpha5beta1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. This compound also inhibits other integrins with IC50 values of 380 nM (alphanubeta3), 280 nM (alphanubeta5), 230 nM (alphanubeta6), and 87...
| CAS | 2234874-68-9 |
| MW: | 506.64 D |
Please request pricing for this article.
CRF1 receptor antagonist-1
Item number: TGM-T79793-50mg
Description: CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1]. Target: CFTR
| CAS | 2635364-30-4 |
| MW: | 499.04 D |
Please request pricing for this article.
TNIK&MAP4K4-IN-1
Item number: TGM-T79794-50mg
Description: TNIK&MAP4K4-IN-1 (compound A-39) is a potent dual inhibitor of TNIK and MAP4K4/HGK, with IC50 values of 1.29 nM and <10 nM, respectively, in human hepatic stellate cell LX-2, and is applicable in cancer and fibrosis inhibition [1]. Target: Others
| CAS | 2478592-86-6 |
| MW: | 446.47 D |
Please request pricing for this article.