7-Acetoxy-4-methylcoumarin

7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase and acetylcholinesterase (AChE). Upon hydrolysis of 7-acetoxy-4-methylcoumarin by carboxylic esterase or AChE, the fluorescent moiety 4-methylumbelliferyl (4-MU) is released, which displays pH-dependent excitation maxima of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm. 7-Acetoxy-4-methylcoumarin has been used to detect the presence of carboxylesterases in isolated human lung tissue.Formal Name: 7-(acetyloxy)-4-methyl-2H-1-benzopyran-2-one. CAS Number: 2747-05-9. Synonyms: 4-Methylumbelliferyl Acetate, 4-MUA, NSC 1059, NSC 31658, NSC 44763, NSC 688806. Molecular Formula: C12H10O4. Formula Weight: 218.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml. SMILES: O=C1OC2=C(C(C)=C1)C=CC(OC(C)=O)=C2. InChi Code: InChI=1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3. InChi Key: HXVZGASCDAGAPS-UHFFFAOYSA-N.