6-Methylmercaptopurine-d3

6-Methylmercaptopurine-d3 (6-MMP-d3) is intended for use as an internal standard for the quantification of 6-MMP (Cay-34356) by GC- or LC-MS. 6-MMP is a metabolite of the purine synthesis and interconversion inhibitor 6-mercaptopurine (6-MP, Cay-23675). It is formed from 6-MP via methylation by thiopurine S-methyltransferase. Levels of 6-MMP are increased in patients with altered thiopurine metabolism and associated with therapeutic resistance to 6-MP.Formal Name: 6-(methyl-d3-thio)-9H-purine. CAS Number: 33312-93-5. Synonyms: 6-MMP-d3, 6-(Methylthio)purine-d3. Molecular Formula: C6H3D3N4S. Formula Weight: 169.2. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMF: 15 mg/ml, DMSO: 30 mg/ml. SMILES: [2H]C([2H])([2H])SC1=C2C(N=CN2)=NC=N1. InChi Code: InChI=1S/C6H6N4S/c1-11-6-4-5(8-2-7-4)9-3-10-6/h2-3H,1H3,(H,7,8,9,10)/i1D3. InChi Key: UIJIQXGRFSPYQW-FIBGUPNXSA-N.