5-iodo A-85380 (hydrochloride)
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Larger quantity required? Request bulk
An agonist of alpha4beta2 and alpha6beta2 subunit-containing nAChRs, activates alpha-conotoxin... more
Product information "5-iodo A-85380 (hydrochloride)"
An agonist of alpha4beta2 and alpha6beta2 subunit-containing nAChRs, activates alpha-conotoxin MII-sensitive and -insensitive dopamine release in rat striatal synaptosomes, markers of alpha4beta2 and alpha6beta2 subunit-containing nAChR activation, respectively (EC50s = 12.7 and ~35 nM, respectively), decreases the total number of AIMs in a rat model of L-DOPA-induced Parkinson's disease at 0.37 µmol/kg per day. Formulation: A solid. InChI: InChI=1S/C9H11IN2O.2ClH/c10-7-3-9(5-11-4-7)13-6-8-1-2-12-8,,/h3-5,8,12H,1-2,6H2,2*1H/t8-,,/m0../s1. InChIKey: ZJVVFYWEBSHGBV-JZGIKJSDSA-N. SMILES: IC1=CC(OC[C@@H]2CCN2)=CN=C1.Cl.Cl
| Keywords: | 3-[(2S)-2-azetidinylmethoxy]-5-iodo-pyridine, dihydrochloride |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43194 |
Properties
| Application: | alpha4beta2 / alpha6beta2 subunit-containing nAChR agonist |
| MW: | 363 D |
| Formula: | C9H11IN2O . 2HCl |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1217837-17-6| Matching products |
| KEGG ID : | K04813 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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