4-Methylumbelliferyl-beta-D-Glucopyranoside

4-Methylumbelliferyl-beta-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of beta-glucosidase and beta-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel beta-glucosidases, 4-MUG is used in assays to evaluate deficiency in beta- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.Formal Name: 7-(beta-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one. CAS Number: 18997-57-4. Synonyms: 4-MU-GLU, 4-MU-beta-Gluc, 4-MUG, MU-GLU. Molecular Formula: C16H18O8. Formula Weight: 338.3. Purity: >98%. Emission: 445-454 nm. Excitation: 330 nm (pH 4.6), 370 nm (pH 7.4), 385 nm (pH 10.4). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 50 mg/ml. lambdamax: 317 nm. SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C(C(C)=CC(O3)=O)C3=C2)O1. InChi Code: InChI=1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1. InChi Key: YUDPTGPSBJVHCN-YMILTQATSA-N.