112 products were found matching "K00688"!

1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 µM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in...

N6-Methyladenosine 5'-monophosphate is an activator of glycogen phosphorylase b (Ka = 22 µM). It is also a non-competitive inhibitor of rat adenylate kinase II (Ki = 4.2 mM). N6-Methyladenosine 5'-monophosphate (sodium salt) has been used for immunoprecipitation of N6-methyladenosine.Formal Name:...

Description: CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 µM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Target: Phosphorylase. Smiles: CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1. References: Martin WH, et al. Proc Natl Acad...

Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic...

4-Methylumbelliferyl-beta-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of beta-glucosidase and beta-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel beta-glucosidases, 4-MUG is used in assays to evaluate deficiency in beta- glucocerebrosidase activity...

Protein function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. [The UniProt Consortium]

CP 91,149 is an inhibitor of human liver glycogen phosphorylase a (LGPa), muscle glycogen phosphorylase a (MGPa), and MGPb (IC50s = 0.13, 0.2, and 0.3 µM, respectively, in the presence of glucose). CP 91,149 is 5- to 10-fold less potent in the absence of glucose. In vitro, it inhibits glucagon-stimulated...