3-Isomangostin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human... more
Product information "3-Isomangostin"
Description: 3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows antiplasmodial activity with an IC50 values in the range of 4.71-11.40 uM. 3-Isomangostin can be used to develop anticancer agents as well. Target: MTH1. Smiles: COc1c(O)cc2oc3cc4OC(C)(C)CCc4c(O)c3c(=O)c2c1CC=C(C)C. References: In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species. Planta Med. 2014 Jun,80(8-9):676-81.
| Supplier: | TargetMol |
| Supplier-Nr: | T2S1635 |
Properties
| Application: | Bioactive xanthone, MTH1 inhibitor |
| MW: | 410.46 D |
| Formula: | C24H26O6 |
Database Information
| CAS : | 19275-46-8| Matching products |
| KEGG ID : | K17816 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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