3-Deazaadenosine (hydrochloride)

3-Deazaadenosine (3-DZA) is an inhibitor of S-adenosylhomocysteine hydrolase (Ki = 3.9 µM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-kappaB signaling. 3-DZA also has antiviral and antibacterial activities.Formal Name: 1-beta-D-ribofuranosyl-1H-imidazo[4,5-c]pyridin-4-amine, monohydrochloride. CAS Number: 86583-19-9. Synonyms: c3Ado, deaza-Ado, 3-DZA. Molecular Formula: C11H14N4O4 . HCl. Formula Weight: 302.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 215, 263 nm. SMILES: NC1=NC=CC2=C1N=CN2[C@@]3([H])[C@@](O)([H])[C@@](O)([H])[C@](CO)([H])O3.Cl. InChi Code: InChI=1S/C11H14N4O4.ClH/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11,/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13),1H/t6-,8-,9-,11-,/m1./s1. InChi Key: WQRKYGAAEYXMKZ-RPWKAPHTSA-N.