2,4'-Dibromoacetophenone

2,4'-Dibromoacetophenone is an inhibitor of glycogen synthase kinase 3beta (GSK3beta, IC50 = 0.5 µM). It is selective for GSK3beta over protein kinase A (PKA, IC50 = >100 µM). It has also been used in the derivatization of lactic acid and glycolic acid prior to analysis by HPLC.Formal Name: 2-bromo-1-(4-bromophenyl)-ethanone. CAS Number: 99-73-0. Synonyms: GSK-3beta Inhibitor VII, NSC 6224. Molecular Formula: C8H6Br2O. Formula Weight: 277.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 5 mg/ml, DMSO: 2 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): insol. lambdamax: 263 nm. SMILES: O=C(CBr)C1=CC=C(C=C1)Br. InChi Code: InChI=1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2. InChi Key: FKJSFKCZZIXQIP-UHFFFAOYSA-N.