1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)

1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 µM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.Formal Name: 2R-(hydroxymethyl)-3R,4R-pyrrolidinediol, monohydrochloride. CAS Number: 100991-92-2. Synonyms: DAB. Molecular Formula: C5H11NO3 . HCl. Formula Weight: 169.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 10 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: OC[C@H]1NC[C@@H](O)[C@@H]1O.Cl. InChi Code: InChI=1S/C5H11NO3.ClH/c7-2-3-5(9)4(8)1-6-3,/h3-9H,1-2H2,1H/t3-,4-,5-,/m1./s1. InChi Key: PZGVJCJRMKIVLJ-DEVUXVJFSA-N.