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Product information "(+/-)-Verapamil . HCl (USP Grade)"
White powder. Soluble in methanol (50 mg/ml), ethanol or water. alpha1-Adrenergic receptor (alpha-AR) antagonist, Prototypical calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells, Vasodilator known to reduce the renal clearance of digoxin and used to control hypertension, angina, cardiac arrhythmia and vascular headaches, Apoptosis inducer in primary and metastatic colon adenocarcinoma human cell lines in vitro, Inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein) which are often over-expressed in certain tumor cell lines, Substrate of CYP3A4 and CYP2C6, Used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342, Anti-diabetic in animal models by limiting TXNIP expression.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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