Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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Kendomycin (Antibiotic TAN 2162)
Kendomycin (Antibiotic TAN 2162)

Item number: K0152.500

Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and negative bacteria including MRSA strains, also displaying antitumor activity. Kendomycin has been reported to be a potent endothelin receptor agonist and has...
CAS 183202-73-5
MW: 486.65 D
540.00€ *
Review
Kijanimicin (Antibiotic Sch 25663)
Kijanimicin (Antibiotic Sch 25663)

Item number: K1765-30.500

Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitro-aminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor activity. However, several members of this class have received...
CAS 78798-08-0
MW: 1317.50 D
587.00€ *
Review
O-Methylsterigmatocystin
O-Methylsterigmatocystin

Item number: M3388-25.1

O-Methylsterigmatocystin is a xanthone isolated from several species of Aspergillus and Chaetomium. O-Methysterigmatocystin is structurally related to the aflatoxins and while the available data has led it to be considered mutagenic, teratogenic and carcinogenic, it is less widespread and potent than the aflatoxins....
CAS 17878-69-2
MW: 338,3 D
412.00€ *
Review
Mycophenolic Acid (Melbex, Lilly 68618, NSC 129185)
Mycophenolic Acid (Melbex, Lilly 68618, NSC 129185)

Item number: M9580-16E.25

Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation has shown mycophenolic acid to display a broad range of pharmacological activities including antitumor, antiviral, antifungal and antiprotozoan activities. However, it was the discovery that...
CAS 24280-93-1
MW: 320,3 D
380.00€ *
Review
Oligomycin B
Oligomycin B

Item number: O6154-01.5

Oligomycin B, a minor component of the oligomycin complex isolated from selected strains of Streptomyces sp., is an inhibitor of mitochondrial F1F0-ATPase. It makes cells more susceptible to cell death and also leads to a switch in the death mode from apoptosis to necrosis. Related to: Oligomycin A, Oligomycin C,...
Application: F1F0-ATPase inhibitor
CAS 11050-94-5
MW: 805,1 D
412.00€ *
Review
Ophiobolin C (Zizzanin A)
Ophiobolin C (Zizzanin A)

Item number: O7024-02.1

Ophiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris. Ophiobolin C is an inhibitor of human CCR5 binding to the envelope protein gp120 and CD4 that mediates HIV-1 viral entry into cells. Blockade of this binding was considered by scientists at...
CAS 19022-51-6
MW: 386,6 D
715.00€ *
Review
Ostreogrycin A (Mikamycin A, Pristinamycin IIA, Stephylo
Ostreogrycin A (Mikamycin A, Pristinamycin IIA, Stephylo

Item number: O8070-50.5

Ostreogrycin A also commonly referred to as virginiamycin M1 or streptogramin A is the major component of the "virginamycin complex". In the 1950s this complex was independently discovered so many times the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts...
CAS 21411-53-0
MW: 525.60 D
587.00€ *
Review
Paraherquamide E (Antibiotic VM 54159, 14-Deoxy-paraherq
Paraherquamide E (Antibiotic VM 54159, 14-Deoxy-paraherq

Item number: P3106-82.500

Paraherquamide E is a member of the paraherquamide family which cause a potent non-toxic paralysis of nematodes and has led to the investigation of their potential as anthelmintics. Although paraherquamide A has received more attention, paraherquamide E has been shown to be the more potent anthelmintic in vivo....
CAS 125600-53-5
MW: 477.60 D
659.00€ *
Review
Pleuromutilin (Drosophilin B, Antibiotic A 40104C)
Pleuromutilin (Drosophilin B, Antibiotic A 40104C)

Item number: P4270-90.25

Pleuromutilin is a diterpene produced by several species of basidomycetes, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria with no cross resistance to existing antibiotic classes due to its unique mode of...
CAS 125-65-5
MW: 378,5 D
636.00€ *
Review
Prodigiosin
Prodigiosin

Item number: P9005-85.500

Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably, Serratia marcescens. Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria. It was shown to be an immunosuppressant in 2007. The mode of action of prodigiosin has recently...
CAS 82-89-3
MW: 323,4 D
587.00€ *
Review
Puromycin Aminonucleoside (3'-Dimethylamino-3'-deoxyadenosine)
Puromycin Aminonucleoside...

Item number: P9200-02.10

Puromycin aminonucleoside is a semi-synthetic derivative of puromycin lacking the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis but exhibits antitumor properties....
CAS 58-60-6
MW: 294,3 D
380.00€ *
Review
Resistoflavine (Antibiotic A 3733Y, Resistoflavin)
Resistoflavine (Antibiotic A 3733Y, Resistoflavin)

Item number: R1589-01.1

Resistoflavine is a rare, boat-shaped, pentacyclic polyketide isolated from several species of Streptomyces, often co-produced with resistomycin. Resistoflavine exhibits weak antibiacterial activity against Gram postive and Gram negative bacteria and exhibits potent cytotoxic activity against tumor cell lines in...
CAS 29706-96-5
MW: 392,4 D
540.00€ *
Review
65 from 67 pages