Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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Berninamycin D
Berninamycin D

Item number: B1078-75D.500

Berninamycin D is an antibiotic discovered in 1994 isolated from a strain of Streptomyces as a minor analogue of berninamycin A. Berninamycin D is a macrocyclic "peptide" comprising atypical amino acids linked to thiazole and oxazoles but does not contain the didehydroalaninyl side chain present in other members of...
CAS 161263-50-9
MW: 1008.00 D
587.00€ *
Review
Blasticidin A
Blasticidin A

Item number: B2104.1

Blasticidin A is a high molecular weight tetramic acid with broad spectrum antifungal and antibacterial activity, first reported in 1955. Like many tetramic acids, blasticidin A is isolated as the stable calcium salt/complex. Blasticidin A and closely related aflastatin A are specific inhibitors of the production of...
CAS 100513-53-9
MW: 1186.50 D
780.00€ *
Review
Cerulenin (Helicocerin, NSC 116069, 2,3-Epoxy-4-oxo-7,10-dodecadienamide)
Cerulenin (Helicocerin, NSC 116069,...

Item number: C2890.5

Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens and identified as an antifungal in the 1960s. Over the past 40 years cerulenin has found broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to B-keto-acyl-ACP synthase...
CAS 17397-89-6
MW: 223,3 D
457.00€ *
Review
Chartreusin (Lambdamycin, NSC 5159, Antibiotic 747, Anti
Chartreusin (Lambdamycin, NSC 5159, Antibiotic 747, Anti

Item number: C3800.5

Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also potent inhibitor of topoisomerase II. , , DMSO and DMF, partially...
CAS 6377-18-0
MW: 640.60 D
478.00€ *
Review
Cycloechinulin
Cycloechinulin

Item number: C8505-20.1

Cycloechinulin is an unusual diketopiperazine isolated from Aspergillus ochraceus. Cycloechinulin has not been extensively studied but has been reported to exhibit insecticidal activity against the lepidopteran crop pest Helicoverpa zea. Recently, cycloechinulin has found use a secondary metabolite standard for...
CAS 143086-29-7
MW: 351,4 D
508.00€ *
Review
Enniatin complex
Enniatin complex

Item number: E3222-30.10

Enniatins are a complex of depsipeptides produced by several Fusarium species. Typically, the complex contains 4 major components: A, A1, B and B1 together with minor amounts of enniatin C, D, E and F. The enniatins have been shown to act as ionophores. Recently, their effects on acyl-CoA cholesterol transferase, as...
CAS 11113-62-5
MW: 639,8 D
587.00€ *
Review
Herbimycin A, dihydro- (Antibiotic TAN 420E, Antibiotic
Herbimycin A, dihydro- (Antibiotic TAN 420E, Antibiotic

Item number: H2030-35A1.500

Antibiotic TAN 420E is the hydroquinone analogue of herbimycin A. It has been patented as an antibacterial, antifungal and antiprotozoan active. The study of Antibiotic TAN 402E has been over-shadowed by the more readily accessible quinone. Little is known of the selectively of the hydroquinone's biological profile...
CAS 91700-93-5
MW: 576.70 D
801.00€ *
Review
Herbimycin C (Antibiotic TAN 420D)
Herbimycin C (Antibiotic TAN 420D)

Item number: H2030-35C.500

Herbimycin C is a minor analogue of herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumor activity and has been shown to convert Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access has restricted a full investigation of the...
CAS 91700-92-4
MW: 560.60 D
587.00€ *
Review
Herbimycin C, dihydro- (Antibiotic TAN 420C)
Herbimycin C, dihydro- (Antibiotic TAN 420C)

Item number: H2030-35C1.500

Antibiotic TAN 420C is a minor analogue of Herbimycin complex isolated from Streptomyces hygroscopicus. It is the hydroquinone of herbimycin C which is known to exhibit antitumor activity and has been shown to convert Rous sarcoma virus-infected rat kidney cells into normal cells. Purity: >95% by HPLC , Solubility:...
CAS 91700-91-3
MW: 562.70 D
801.00€ *
Review
Indolmycin (Antibiotic PA 155A)
Indolmycin (Antibiotic PA 155A)

Item number: I0798.1

Indolmycin is a highly selective antibiotic which acts as a tryptophan anti-metabolite. Recent research has shown that indolmycin is active against Mycobacteria and Helicobacter pylori and can stimulate transcription in Escherichia coli. Purity: >99% by HPLC, mixture of diastereoisomers , Solubility: Soluble in...
Keywords: Antibiotic
Application: Mycobacteria inhibition
CAS 21200-24-8
715.00€ *
Review
Ikarugamycin
Ikarugamycin

Item number: I2300-20.500

Ikarugamycin is an unsual pentacyclic tetramic acid produced by Streptomyces phaeochromogenes with potent activity against the protozoan, Trichomonas vaginalis, reported in 1972. Ikarugamycin also demonstrated selective Gram positive antibacterial activity and more recently has been shown to exhibit anti-ulcer...
CAS 36531-78-9
MW: 478,6 D
511.00€ *
Review
Antibiotic K252A (Antibiotic SF 2370)
Antibiotic K252A (Antibiotic SF 2370)

Item number: K0000-50C.500

Antibiotic K252A is a staurosporine analogue isolated from a Nocardiopsis strain as a potent inhibitor of protein kinase C. Antibiotic K252A exhibits potent antitumor activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents. More extensive investigation has demonstrated that while...
CAS 99570-78-2
MW: 453,5 D
478.00€ *
Review
64 from 67 pages