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Ampicillin (hydrate)
Item number: Cay35740-100
Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria, including veterinary isolates of S. pseudintermedius, S. aureus, E. coli, Pasteurella, and S. canis (MIC50s = 0.25, 0.5, 2, 0.12, and 0.25 µg/ml, respectively). In vivo, ampicillin (80 mg/kg, i.v.) reduces cough...
| Keywords: | Aminobenzylpenicillin trihydrate,... |
| Application: | Broad-spectrum antibiotic, antibacterial, cell wall biosynthesis inhibitor |
| CAS | 7177-48-2 |
| MW: | 403.5 D |
From 87.00€
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Lefamulin
Item number: Cay36285-10
Lefamulin is a pleuromutilin antibiotic. It is active against methicillin-resistant S. aureus (MRSA), S. pyogenes, E. faecium, H. influenzae, M. catarrhalis, L. pneumonophilia, C. pneumoniae, and M. pneumoniae (MIC50s = 0.006-1 µg/ml). Lefamulin is also active against fluoroquinolone- and macrolide-resistant strains...
| Keywords: | BC-3781, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-acetic acid,... |
| Application: | Pleuromutilin antibiotic, antibacterial, protein biosynthesis inhibitor |
| CAS | 1061337-51-6 |
| MW: | 507.7 D |
From 154.00€
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Cyclamidomycin
Item number: Cay36387-1
Cyclamidomycin is a bacterial metabolite that has been found in Streptomyces and has antibiotic activity. It is active against S. aureus, M. flavus, S. lutea, B. subtilis, E. coli, S. flexneri, S. typhosa, P. vulgaris, and K. pneumoniae (MICs = 3.12-25 mg/ml). Cyclamidomycin inhibits E. coli nucleoside...
| Keywords: | Desdanine, NSC 121234, Pyracrimycin A, (2E)-3-(3,4-dihydro-2H-pyrrol-5-yl)-2-propenamide |
| Application: | Bacterial metabolite, antibiotic agent |
| CAS | 35663-85-5 |
| MW: | 138.2 D |
1,201.00€
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Minosaminomycin
Item number: Cay36406-1
Minosaminomycin is an antibiotic that has been found in Streptomyces. It is active against M. smegmatis and M. phlei (MICs = 1.56 and 6.25 µg/ml, respectively). Minosaminomycin (1 µM) inhibits the binding of formyl-Met-tRNA (fMet-tRNA) to ribosomes in the presence of the AUG trinucleotide by 96% in a cell-free assay...
| Keywords: | MSM,... |
| Application: | Antibiotic |
| CAS | 51746-09-9 |
| MW: | 618.7 D |
856.00€
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Manumycin A
Item number: AG-CN2-2000-M010
Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect geranylgeranyltransferase (IC50 = 180 µM). Inhibition is competitive with respect to farnesyl pyrophosphate and...
| Keywords: | Posttranslational Mod. |
| Application: | Rasfarnesyltransferase inhibitor |
| CAS | 52665-74-4 |
| MW: | 550.6 D |
792.00€
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Mevastatin
Item number: CDX-M0183-M050
RTECS: EK7907100 Source/Host Chemicals: Synthetic. Appearance: White to light yellow powder. Solubility: Soluble in DMSO or ethanol (20mg/ml). Insoluble in water. Identity: Determined by 1H-NMR. InChi Key: AJLFOPYRIVGYMJ-INTXDZFKSA-N Smiles:...
| Keywords: | Compactin, 6-Demethylmevinolin, CS-500, ML-236B, L-637,312, NSC 281245, Statin I |
| Application: | Antibiotic, competitive HMG-CoA reductase inhibitor |
| CAS | 73573-88-3 |
| MW: | 390.51 D |
73.00€
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GSK2200150A
Item number: Cay36620-1
GSK2200150A is a spirocyclic antimycobacterial agent. It is active against M. tuberculosis and M. bovis (MICs = 0.38 and 1.6 µM, respectively).Formal Name: 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-6',7'-dihydro-spiro[piperidine-4,4'-[4H]thieno[3,2-c]pyran. CAS Number: 1443138-53-1. Molecular Formula: C20H23NO3S....
| Keywords: | 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-6',7'-dihydro-spiro[piperidine-4,4'-[4H]thieno[3,2-c]pyran |
| Application: | Antimycobacterial agent |
| CAS | 1443138-53-1 |
| MW: | 357.5 D |
From 42.00€
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Merafloxacin
Item number: Cay37709-1
Merafloxacin is a fluoroquinolone antibiotic. It is active against various Gram-positive bacteria (MIC50s = 0.12-0.5 µg/ml) and various Gram-negative bacteria (MIC50s = 0.06-1 µg/ml).Formal Name: 1-ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid. CAS Number:...
| Keywords: | Cl 934, 1-ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Application: | Fluoroquinolone antibiotic |
| CAS | 91188-00-0 |
| MW: | 379.4 D |
From 42.00€
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Cyclosporin B
Item number: Cay19525-1
Cyclosporin B is a minor cyclopeptide metabolite produced by T. polysporum and other deuteromycota with diverse biological activities. It inhibits the growth of T lymphoma cells in a concentration-dependent manner. Cyclosporin B also inhibits P-glycoprotein (P-gp) activity in vitro with an IC50 value of 4.7...
| Keywords: | Antibiotic S 7481F2, 7-L-alanine-cyclosporin A |
| Application: | Antibiotic |
| CAS | 63775-95-1 |
| MW: | 1188.6 D |
From 72.00€
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Indanomycin
Item number: Cay21761-1
Indanomycin is an antibiotic of the pyrroloketoindane class, which includes an unusual indane ring structure. It has bactericidal activity against Gram-positive bacteria, with minimum inhibitory concentration (MIC) values of =0.2 µg/ml.Formal Name:...
| Keywords: | X 14547A,... |
| Application: | Antibiotic |
| CAS | 66513-28-8 |
| MW: | 493.7 D |
From 366.00€
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Tetranactin
Item number: Cay26687-1
Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold greater for lithium than sodium or cesium ions accross bilayer membranes at low voltages....
| Keywords: | (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-4,13,22,31,37,3... |
| Application: | Antibacterial, insecticidal, mitogenic macrotetrolide, monovalent cation ionophore |
| CAS | 33956-61-5 |
| MW: | 793 D |
From 299.00€
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Bacitracin A (technical grade)
Item number: Cay36252-1
Bacitracin A is a polypeptide antibiotic that has been found in B. licheniformis and the main active component of the bacitracin family of polypeptide antibiotics. It is active against M. lysodeikticus when used at a concentration of 0.1 µM and forms a complex with divalent cations and the cell membrane component...
| Keywords: | NSC 45737,... |
| Application: | Polypeptide antibiotic |
| CAS | 22601-59-8 |
| MW: | 1422.7 D |
From 137.00€
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