No results were found for the filter!
NEW
MMP Inhibitor III
Item number: Cay45494-1
MMP inhibitor III is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs, IC50s = 4.1, 3.6, 8.2, and 6.4 nM for MMP-1, MMP-2, MMP-12, and MMP-13, respectively). It also inhibits MMP-3 with an IC50 value of 134 nM. MMP inhibitor III reduces ionomycin-induced shedding of CD146 in human microvascular lung...
| Keywords: | Matrix Metalloproteinase Inhibitor III,... |
| Application: | Broad-spectrum MMP inhibitor |
| CAS | 927827-98-3 |
| MW: | 363.46 D |
From 245.00€
*
NEW
Cholesteryl Hemisuccinate (tris salt)
Item number: Cay45505-100
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 µM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize...
| Keywords: | Cholesterol Hemisuccinate, Cholesterol Hydrogen Succinate, Cholesterol Monosuccinate, Succinate Cholesterol Monoester,... |
| Application: | Cholesterol ester, anticancer agent, ionizable anionic detergent, emulsifying agent |
| CAS | 102601-49-0 |
| MW: | 607.87 D |
From 95.00€
*
NEW
Geministatin D
Item number: Cay45510-100
Geministatin D is a degradation product of the fungal metabolite geministatin A. It is active against B. subtilis and S. cerevisiae (MICs = 25 and 13 µg/ml, respectively).. SMILES: OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC(CCCCCCC/C=C\C/C=C\CCCCC)=C(C(O)=O)C(O)=C2)O1. InChi Code:...
| Keywords: | 2-(-heptadeca-8Z,11Z-dien-1-yl)-6-hydroxy-4-(((2S)-3R,4S,5R-trihydroxy-6R-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benz... |
| Application: | Geministatin A degradation product |
| MW: | 550.69 D |
From 191.00€
*
NEW
Turonicin A
Item number: Cay45511-1
Turonicin A is a polyketide synthase-derived linear polyene originally isolated from Streptomyces that has antifungal and antibacterial activities. It is active against C. albicans, S. cerevisiae, B. subtilis, and S. aureus (MICs = 2.7, 0.7, 85, and 340 nM, respectively).. SMILES:...
| Keywords: | (2E,4E,6E,8E,12E,14S,15S,16S,17R,18E,20E,22E,24E,26E,29S,30S,33R,35S,37S,38E,41R,43S,45R,47S,48E,51S,52E,55R)-58-guanidino... |
| Application: | Polyketide, antifungal / antibacterial agent |
| CAS | 3059457-35-8 |
| MW: | 1138.49 D |
From 355.00€
*
NEW
Glenthmycin J
Item number: Cay45512-1
Glenthmycin J is a macrocyclic spirotetronate originally isolated from Streptomyces.. SMILES: OC([C@@]12[C@@](/C=C(CC/C=C([C@@]3([H])[C@@]4([C@@]5([H])[C@]([C@H](CC[C@@H]5C)O)([H])C=C3C)C)\C)\C)([H])C=C([C@@H](C1)C)C)=C(C(O2)=O)C4=O. InChi Code:...
| Keywords: | (1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,19E,20aS,20bR)-4,21-dihydroxy-1,6,7,11,14,15,20a-heptamethyl-2,3,4,4a,6a,9,10,12a,15,1... |
| Application: | Macrocyclic spirotetronate |
| CAS | 3040055-89-5 |
| MW: | 520.71 D |
From 355.00€
*
NEW
Glenthmycin L
Item number: Cay45513-1
Glenthmycin L is a macrocyclic spirotetronate originally isolated from Streptomyces that has antibacterial activity. It is active against S. aureus, methicillin-resistant S. aureus (MRSA), and E. faecalis (IC50s = 1.2, 0.9, and 3.7 µM, respectively).. SMILES:...
| Keywords: | (1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,19E,20aS,20bR)-21-hydroxy-1,6,7,11,14,15,20a-heptamethyl-18,20-dioxo-1,2,3,4,4a,6a,9,1... |
| Application: | Macrocyclic spirotetronate, antibacterial agent |
| CAS | 3040055-91-9 |
| MW: | 562.75 D |
From 249.00€
*
NEW
Liraglutide
Item number: Cay45521-1
Liraglutide is an agonist of the glucagon-like peptide 1 receptor (GLP-1R) and a synthetic derivative of GLP-1 (7-37, Item No. 24887). It increases cAMP accumulation in BHK cells expressing GLP-1R (EC50 = 61 pM). Liraglutide (100-1,000 nM) inhibits cytokine- and free fatty acid-induced apoptosis of primary neonatal...
| Keywords: | NN 2211, NNC 90-1170, L-histidyl-L-alanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenyla... |
| Application: | GLP-1R agonist |
| CAS | 204656-20-2 |
| MW: | 3751.26 D |
From 47.00€
*
NEW
Bisphenol S
Item number: Cay45556-1
Bisphenol S (BPS) is a derivative of bisphenol A (BPA), an environmental contaminant, and an endocrine disruptor. It has been detected in surface water and sewage effluent and in personal care products, paper, and food. BPS increases estrogenic activity in vitro, in female rats, and in male and female zebrafish. It...
| Keywords: | 4,4'-Sulfonyldiphenol, Bis(4-hydroxyphenyl)sulfone, BPS, NSC 683541, NSC 8712, 4,4'-sulfonylbis-phenol |
| Application: | BPA derivative, environmental contaminant, endocrine disruptor |
| CAS | 80-09-1 |
| MW: | 250.27 D |
From 35.00€
*
NEW
Bisphenol F
Item number: Cay45557-10
Bisphenol F (BPF) is a derivative of bisphenol A (BPA), an environmental contaminant, and an endocrine disruptor. It has been detected in personal care products, wastewater treatment sludge, bottled water, and canned foods. BPF has estrogenic activity in vitro and in female rats. It also has neurotoxic effects,...
| Keywords: | 4,4'-Dihydroxydiphenylmethane, BPF, NSC 401136, 4,4'-methylenebis-phenol |
| Application: | BPA derivative |
| CAS | 620-92-8 |
| MW: | 200.24 D |
From 119.00€
*
NEW
3BrB-PP1
Item number: Cay45582-10
3BrB-PP1 is a bumped kinase inhibitor (BKI) that acts as a selective, ATP-competitive inhibitor of kinases with gatekeeper mutations. It increases the activity of the T. gondii bradyzoite-specific BAG1 promoter. 3BrB-PP1 has been used to study kinase activity using kinases containing mutations at gatekeeper residues...
| Keywords: | 3-[(3-bromophenyl)methyl]1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Application: | Bumped kinase inhibitor |
| CAS | 956025-99-3 |
| MW: | 360.26 D |
From 235.00€
*
NEW
6,6'-Oxybis(2-naphthalenesulfonate) (sodium salt)
Item number: Cay45595-1
6,6'-Oxybis(2-naphthalenesulfonate) is a byproduct in the synthesis of FD&C Yellow No. 6 and FD&C Red No. 40 (Allura Red AC, Item No. 44514). It is formed during the synthesis of Schaeffer's salt, an intermediate used in the synthesis of FD&C Yellow No. 6. 6,6'-Oxybis(2-naphthalenesulfonate) is also an impurity...
| Keywords: | DONS, 6,6'-oxybis-2-naphthalenesulfonic acid, disodium salt |
| Application: | Food dye synthesis byproduct |
| CAS | 61551-82-4 |
| MW: | 474.4 D |
From 153.00€
*
NEW
Myristoyl Tetrapeptide-12 (acetate)
Item number: Cay45604-10
Myristoyl tetrapeptide-12 is a polymeric acylated biosurfactant. It has a critical micelle concentration of less than 200 ppm in aqueous minimal essential media (MEM) and is active against E. coli, C. albicans, P. aeruginosa, and S. aureus (MICs = =100 ppm). Formulations containing myristoyl tetrapeptide-12 have...
| Keywords: | Myr-Lys-Ala-Lys-Ala-NH2, N2-(1-oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide, acetate |
| Application: | Polymeric acylated biosurfactant |
| MW: | 625.9 D |
From 42.00€
*