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![Physiological Saline [Sodium Chloride 0.9%] Endotoxin-free Sterile Solution](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Physiological Saline [Sodium Chloride 0.9%] Endotoxin-free Sterile Solution")
Physiological Saline [Sodium Chloride 0.9%]...
Item number: IAX-900-003-L100
Use for the dilution of TLRpureTM LPS and solubilisation of endotoxin-free reagents (e.g. ODNs).
| Keywords: | Sodium Chloride 0.9% |
| CAS | 7647-14-5 |
From 34.00€
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MLN4924
Item number: Cay15217-1
NEDD8 is an ubiquitin-like protein whose activity is required to activate cullin-RING ubiquitin E3 ligases (CRLs) responsible for the ubiquitination and proteasome-dependent turnover of certain substrates with roles relevant to cellular processes important for cancer cell survival. Neddylation of CRLs is initiated...
| Keywords: | Pevonedistat, sulfamic acid,... |
| Application: | Adenosine 5'-monophosphate analog, NAE inhibitor |
| CAS | 905579-51-3 |
| MW: | 443.5 D |
From 82.00€
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(2R)-Octyl-alpha-hydroxyglutarate
Item number: Cay16366-10
alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
| Keywords: | (2R)-Octyl-2-HG, 2R-hydroxy-pentanedioic acid, 1-octyl ester |
| CAS | 1391194-67-4 |
| MW: | 260.3 D |
From 55.00€
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15(S)-HETE-d8
Item number: Cay334720-25
15(S)-HETE-d8 is intended for use as an internal standard for the quantification of 15(S)-HETE (Cay-34720) by GC- or LC-MS. (±)15-HETE and 15(S)-HETE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), respectively. 15(R)-HETE is formed by...
| Keywords: | 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 84807-87-4 |
| MW: | 328.5 D |
From 273.00€
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Trichostatin A
Item number: Cay89730-1
Trichostatin A is a potent, reversible inhibitor of class I, II, and IV histone deacetylases (HDACs). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of HDAC1 with an IC50 value of 70 nM. Trichostatin A selectively inhibits the removal of acetyl groups from the...
| Keywords: | TSA, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide |
| Application: | HDAC inhibitor |
| CAS | 58880-19-6 |
| MW: | 302.4 D |
From 91.00€
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(+)-Etomoxir (sodium salt)
Item number: Cay11969-5
(+)-Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT1), an enzyme that combines fatty acyl-CoAs with carnitine for transport into the mitochondria for beta-oxidation. It inhibits fatty acid oxidation in hepatocytes in vitro (IC50s = 0.1, 1, and 10 µM for human, guinea pig, and rat...
| Keywords: | (R)-(+)-Etomoxir, (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylic acid monosodium salt |
| Application: | Irreversible CPT1 / carnitine O-palmitoyltransferase 1 inhibitor |
| CAS | 828934-41-4 |
| MW: | 320.7 D |
From 122.00€
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Nocodazole
Item number: Cay13857-5
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
| Keywords: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Application: | Microtubule function studies, cell cycle arrest |
| CAS | 31430-18-9 |
| MW: | 301.3 D |
From 57.00€
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Psilocin
Item number: Cay11864-50
Psilocin (Cay-11864) is an analytical reference standard categorized as a tryptamine. Psilocin is the active metabolite of the psychedelic compound psilocybin (Cay-9003134, Cay-14041) and the synthetic tryptamine 4-acetoxy DMT (psilacetin, Cay-14056, Cay-35188). It induces the head-twitch response (HTR) in mice,...
| Keywords: | 4-hydroxy DMT, 4-hydroxy-N,N-Dimethyltryptamine, 3-[2-(dimethylamino)ethyl]-1H-indol-4-ol |
| Application: | Analytical reference standard, tryptamine, psilocybin active metabolite |
| CAS | 520-53-6 |
| MW: | 204.3 D |
1,086.00€
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L-Methionine
Item number: Cay31721-100
L-Methionine is an essential amino acid. It is catabolized by methionine adenosyltransferase 2A (MAT2A), yielding the universal methyl donor S-adenosyl-L-methionine (SAM, Cay16376, Cay17595). L-methionine has roles in purine and pyrimidine synthesis, polyamine synthesis, and glutathione production, as well as in...
| Keywords: | (S)-Methionine |
| Application: | Essential amino acid |
| CAS | 63-68-3 |
| MW: | 149.21 D |
From 45.00€
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DNPH1i
Item number: Cay38531-1
DNPH1i is an inhibitor of 2'-deoxynucleotide 5'-phosphate N-hydrolase 1 (DNPH1). It inhibits DNPH1 activity toward the DNPH1 substrate 5-hydroxymethyl-2'-deoxyuridine (hmdU) when used at a concentration of 100 µM. DNPH1i (0.3 µM) reduces the viability of BRCA1-deficient SUM149 cells containing single-guide RNA...
| Keywords: | 2'-Deoxynucleotide 5'-Phosphate N-hydrolase 1 Inhibitor, Benzyladenine Riboside, N6-Benzyladenosine, NSC 70423,... |
| Application: | DNPH1 inhibitor |
| CAS | 4294-16-0 |
| MW: | 357.36 D |
From 98.00€
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(±)-Mesembrenol
Item number: Cay40470-1
(±)-Mesembrenol is an alkaloid that has been found in S. tortuosum and has diverse biological activities. It binds to the serotonin transporter (SERT) with a Ki value of 62 nM. (±)-Mesembrenol reduces single-shock- and theta burst-stimulated population spike amplitudes in rat hippocampal slices. It also reduces...
| Keywords: | (6S)-3a-(3,4-dimethoxyphenyl)-1-methyl-2,3,3a,6,7,7a-hexahydro-1H-indol-6-ol |
| Application: | Bioactive, serotonin transporter (SERT) binding alkaloid |
| MW: | 289.37 D |
From 551.00€
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N-Propionitrile Brorphine (hydrochloride)
Item number: Cay42297-1
N-Propionitrile brorphine (hydrochloride) (Cay42297) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.. SMILES: CC(C1=CC=C(Br)C=C1)N2CCC(N3C(N(CCC#N)C4=C3C=CC=C4)=O)CC2.Cl. InChi Code:...
| Keywords: | 3-(3-(1-(1-(4-bromophenyl)ethyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanenitrile, monohydrochloride |
| Application: | Analytical reference standard, structurally similar to known opioids |
| MW: | 489.84 D |
From 123.00€
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