Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line

Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82729 2 vials - -

3 - 15 business days*

9,897.00€
 
The Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line is a... more
Product information "Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line"
The Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line is a HEK293 cell line stably expressing the full-length human muscarinic acetylcholine receptor M5 (CHRM5/HM5/M5, accession number: AF498919) and a firefly luciferase reporter under the control of the NFAT (nuclear factor of activated T cells) response element. This cell line has been validated by flow cytometry and for its responses to the muscarinic acetylcholine receptor agonists Oxotremorine M and Carbamoylcholine chloride (carbachol). Luciferase activity increases in proportion to mAChR activation. Figure 1: Diagram illustrating the mechanism of action of Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line. Interested in screening and profiling inhibitors, blocking antibodies, or activators of M5 related signaling without the need to purchase and license the cell line? Check out our Cell Signaling Pathway Screening.
Keywords: CHRM5, Muscarinic acetylcholine receptor M5,
Supplier: BPS Bioscience
Supplier-Nr: 82729

Properties

Application: Activator/inhibitor screening, drug discovery
Species reactivity: human

Handling & Safety

Storage: Liquid nitrogen
Shipping: -80°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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