34 products were found matching "K04133"!

Muscarinic acetylcholine receptors belong to a superfamily of seven-TM-domain receptors that interact with G-proteins to initiate intracellular responses. Five muscarinic receptor subtypes have been identified, named M1 through M5. Receptors of the M5 receptor subtype couple through the Gq/11 class of G-proteins and...

An antispasmodic agent.

Protein function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. [The UniProt Consortium]

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Five subtypes (M1-5) have been identified, which preferentially couple to various effector systems based on their G protein interaction.Tropicamide is a muscarinic acetylcholine receptor (mAChR) antagonist (pKi = 7.2 in...

L-type Ca2+ channel blocker, BK K+ channel modulator, potential opioid agonist.

Procyclidine is a synthetic anticholinergic agent and atropine-like antispasmodic. It exhibits therapeutic effects against parkinson's disease and schizophrenia. Procyclidine is an antagonist of muscarinic acetylcholine receptors (Kis = 4.47, 42.66, 7.24, 6.03, and 4.79 nM for M1-5 receptors, respectively). It also...

Protein function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. [The UniProt Consortium] Buffer: 40%...

VU0238429 is a positive allosteric modulator of M5 muscarinic acetylcholine receptors (mAChRs, EC50 = 1.16 µM in a calcium mobilization assay). It is selective for M5 mAChRs over M1, M2, M3, and M4 mAChRs in CHO cells expressing the human receptors (EC50s = >30 µM for all in calcium mobilization assays). VU0238429...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 215-443aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RIYRETEKRT KDLADLQGSD SVTKAEKRKP AHRALFRSCL RCPRPTLAQR ERNQASWSSS RRSTSTTGKP SQATGPSANW AKAEQLTTCS SYPSSEDEDK PATDPVLQVV YKSQGKESPG EEFSAEETEE TFVKAETEKS...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRM5. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRM5. Antigen Species: Human