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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| BPS-82201 | 2 vials | - | - |
3 - 8 business days* |
14,750.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The Full Length Notch1/CSL Luciferase Reporter HEK293 Cell Line is a HEK293 cell line that... more
Product information "Full Length Notch1/CSL Luciferase Reporter HEK293 Cell Line"
The Full Length Notch1/CSL Luciferase Reporter HEK293 Cell Line is a HEK293 cell line that expresses the firefly luciferase reporter under the control of Notch-response elements (CSL responsive elements) and full-length Notch1 (accession number: NM_017617.5). Upon ligand-receptor interaction, the Notch1 receptor is cleaved by gamma-secretase. This active Notch1 NICD (Notch intracellular domain) translocate to the nucleus and induces the expression of the luciferase reporter. The cell line was functionally validated for both activation and inhibition of the expression of luciferase reporter with DAPT and DLL4
| Keywords: | TAN1, NOTCH1, |
| Supplier: | BPS Bioscience |
| Supplier-Nr: | 82201 |
Properties
| Application: | Notch1 antibody/inhibitor screening/validation, drug discovery, immunotherapy research, binding assays |
| Species reactivity: | human |
Database Information
| KEGG ID : | K02599 | Matching products |
| UniProt ID : | P46531 | Matching products |
| Gene ID : | GeneID 4851 | Matching products |
Handling & Safety
| Storage: | Liquid nitrogen |
| Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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