Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set

Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-46B-0008-KI01 1 set - -

3 - 9 business days*

704.00€
 
Detects human Zinc-?-2-glycoprotein. Does not detect mouse Zinc-?-2-glycoprotein. Contains... more
Product information "Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set"
Detects human Zinc-?-2-glycoprotein. Does not detect mouse Zinc-?-2-glycoprotein. Contains sufficient materials to run ELISAs on 5 x 96-well plates. Sensitivity: 100 pg/ml. Range: 0.0156 to 1 ng/ml. Sample Type: Cell Culture Supernatant, Plasma, Serum. Assay Type: Sandwich. Detection Type: Colorimetric. Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
Keywords: ZAG, AZGP1, Zn-alpha-2-GP, Zn-alpha-2-glycoprotein, Zinc-alpha-2-glycoprotein
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-46B-0008

Properties

Application: ELISA
Reactivity: Human
Format: Solid Phase

Database Information

UniProt ID : P25311 | Find alternatives
Gene ID GeneID 563 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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