PAD4 Autoantibody ELISA Kit

PAD4 Autoantibody ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay500930-96 96 wells

1 - 10 business days

532.00€
 
Protein arginine deiminase 4 (PAD4) is a guanidino-modifying enzyme which catalyzes the... more
Product information "PAD4 Autoantibody ELISA Kit"
Protein arginine deiminase 4 (PAD4) is a guanidino-modifying enzyme which catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. PAD4 activity is increased in rheumatoid arthritis (RA), producing citrulline-containing proteins (CCP) that induce the formation of arthritogenic autoantibodies. In addition to anti-CCP autoantibodies, 23-45% of RA patients also produce autoantibodies specific for the PAD4 enzyme itself. Cayman's PAD4 Autoantibody ELISA Kit is an immunometric assay which can be used to measure anti-PAD4 autoantibodies of any isotype (IgM, IgG, and IgA) in human plasma and serum without prior sample purification. Affinity-purified anti-PAD4 antibody isolated from the plasma of a patient with RA is used as the standard. One unit is approximately equal to 1 ng of anti-PAD4 Ig protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 31.3 U/ml.
Keywords: PADI5, PADI4, HL-60 PAD, EC=3.5.3.15, Peptidylarginine deiminase IV, Protein-arginine deiminase type-4, Protein-arginine deiminase type IV Autoantibody kit, Citrullination
Supplier: Cayman Chemical
Supplier-Nr: 500930-96

Properties

Application: ELISA
Reactivity: Human
Format: Solid Phase

Database Information

KEGG ID : K01481 | Search using KEGG ID
UniProt ID : Q9UM07 | Search using UniProt ID

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H314, H315, H317, H318, H319, EUH032
P Phrases: P260, P261, P264, P270, P272, P280, P312, P321, P363, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P332+P313, P333+P313, P337+P313, P362+P364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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