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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
143989.96 | 96 tests | - | - |
3 - 19 business days* |
947.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Sandwich ELISA quantitative detection kit for Mouse Neprilysin/CD10 in cell culture supernates,... more
Product information "Neprilysin/CD10 BioAssay(TM) ELISA Kit, Mouse"
Sandwich ELISA quantitative detection kit for Mouse Neprilysin/CD10 in cell culture supernates, serum and plasma (heparin, EDTA). Neprilysin, also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), CD10, and common acute lymphoblastic leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease, this gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, Neprilysin is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. Neprilysin has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system. , Assay Range:, 93.7pg/ml-6000pg/ml, Sensitivity: < 10 pg/ml, Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: Q61391, Entrez Gene ID: 17380, Kit Components: 96-well plate pre-coated with anti-Neprilysin/CD10, Mouse, Lyophilized recombinant Neprilysin/CD10, Mouse standard, 10ng/tube, 2Ea, USB Cat No Kit Component, 143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution), 143697 Sample diluent buffer, 30ml, 143698 Antibody diluent buffer, 12ml, 143699 ABC diluent buffer, 12ml, 143700 TMB color developing agent, 10ml, 143701 TMB stop solution, 10ml, Storage and Handling: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
Keywords: | Mme, NEP, SFE, CD10, Neprilysin, Enkephalinase, Atriopeptidase, Neutral endopeptidase, Skin fibroblast elastase, Neutral endopeptidase 24.11 |
Supplier: | United States Biological |
Supplier-Nr: | 143989 |
Properties
Application: | ELISA |
Species reactivity: | mouse |
Format: | Solid Phase |
Database Information
KEGG ID : | K01389 | Matching products |
UniProt ID : | Q61391 | Matching products |
Gene ID | GeneID 17380 | Matching products |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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