Mouse Tyrosinase (TYR) ELISA kit

Sample Types: serum, plasma, tissue homogenates, cell lysates Detection Range: 31.25 pg/mL-2000 pg/mL Sensitivity: 7.8 pg/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds (PubMed:2517217). Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (PubMed:2517217, PubMed:1537333). In addition to hydroxylating tyrosine to DOPA (3, 4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5, 6- dihydroxyindole) to indole-5, 6 quinone (PubMed:1537333). [The UniProt Consortium]