144 products were found matching "K00505"!

Isolated from Fusarium graminearum. Monomer of aurofusarin. Mycotoxin. Anticancer and antimycobacterial compound in vivo. Moderate tyrosinase inhibitor. Anti-estrogenic.

Azelaic acid is a naturally occurring and saturated dicarboxylic acid with diverse biological activities. It is a competitive inhibitor of tyrosinase, NADH dehydrogenase, succinic dehydrogenase, and reduced ubiquitinone:cytochrome C oxidoreductase in vitro. Azelaic acid inhibits the growth and colony formation of...

Description: 1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxidant activity, can reduce neuronal oxidative damage and protect hepatocytes against...

Resveratrol is a potent phenolic antioxidant found in the skin of grapes and red wine that has anti-proliferative, anti-inflammatory, and cardioprotective properties. Oxyresveratrol is a naturally occurring analog of resveratrol found in mulberry wood. It effectively scavenges H2O2, NO (IC50 = 45.3 µM), and the...

5,6-dihydroxy Indole is an intermediate in melanogenesis. Its precursor is dopachrome. 5,6-dihydroxy Indole can be metabolized to either eumelanin or pheomelanin, depending, in part, on the availability of cysteine.Formal Name: 1H-indole-5,6-diol. CAS Number: 3131-52-0. Synonyms: Dopamine lutine. Molecular Formula:...

In 1X PBS, pH 7.4, with 0.09% sodium azide. TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous...

Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase. It decreases growth of Leishmania parasites in vitro and in vivo, and it protects mice from damage induced by gamma irradiation. Kojic acid has been used as a...

Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 µM for mushroom tyrosinase). It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 µM. Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits...

White solid. Soluble in DMSO, methanol or water. Mycotoxin. Chelation agent with polyfunctional skeleton for development of biologically active compounds, Moderate antibacterial agent, Tyrosinase inhibitor. Inhibits catecholase activity of tyrosinase, Anti-melanogenic. Skin whitening agent, Antioxidant. Reactive...

Protein function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. [The UniProt Consortium]