Mouse Proto-oncogene Wnt-3 (WNT3) ELISA kit

Sample Types: serum, plasma, tissue homogenates, cell lysates Detection Range: 39 pg/ml-2500 pg/ml Sensitivity: 9.75 pg/ml Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis (PubMed:10431240). Required for normal formation of the apical ectodermal ridge and for normal embryonic limb development (PubMed:12569130). [The UniProt Consortium]