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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG81935.96 | 96 wells | - |
6 - 14 business days* |
1,048.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix... more
Product information "Human TYRO3 ELISA Kit"
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. [The UniProt Consortium]
Keywords: | BYK, TYRO3, EC=2.7.10.1, Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, Tyrosine-protein kinase DTK, Tyrosine-protein kinase SKY, Tyrosine-protein kinase BYK, Tyrosine-protein kinase receptor TYRO3 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG81935 |
Properties
Application: | ELISA |
Species reactivity: | human |
Format: | Solid Phase |
Database Information
KEGG ID : | K05116 | Matching products |
UniProt ID : | Q06418 | Matching products |
Gene ID | GeneID 7301 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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