Human KEAP1(kelch-like ECH-associated protein 1) ELISA Kit

Human KEAP1(kelch-like ECH-associated protein 1) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HUFI03108.96 96 assays -

9 - 20 business days*

698.00€
 
Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed... more
Product information "Human KEAP1(kelch-like ECH-associated protein 1) ELISA Kit"
Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. [The UniProt Consortium]
Keywords: INRF2, KEAP1, INrf2, Kelch-like protein 19, Cytosolic inhibitor of Nrf2, Kelch-like ECH-associated protein 1
Supplier: Assay Genie
Supplier-Nr: HUFI03108

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