Human EPAC1 (Exchange protein directly activated by cAMP 1) ELISA Kit (HUFI07944)

Human EPAC1 (Exchange protein directly activated by cAMP 1) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human EPAC1 (Exchange protein directly activated by cAMP 1) in serum, plasma & cell culture supernatant samples. The Human EPAC1 (Exchange protein directly activated by cAMP 1) ELISA Kit accurately measures natural Human EPAC1 (Exchange protein directly activated by cAMP 1) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Human EPAC1 (Exchange protein directly activated by cAMP 1) peptide. Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP- induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. [The UniProt Consortium]