Bovine MMP13 (Matrix Metalloproteinase 13) ELISA Kit (BOFI00148)

Bovine MMP13 (Matrix Metalloproteinase 13) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Bovine MMP13 (Matrix Metalloproteinase 13) in serum, plasma & cell culture supernatant samples. The Bovine MMP13 (Matrix Metalloproteinase 13) ELISA Kit accurately measures natural Bovine MMP13 (Matrix Metalloproteinase 13) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Bovine MMP13 (Matrix Metalloproteinase 13) peptide. Protein function: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. [The UniProt Consortium]