133 products were found matching "K07994"!

Collagenase 3 (also known as MMP-13) is an enzyme that in humans is encoded by the MMP13 gene. Most MMP's are secreted as inactive pro-proteins, which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. Mitchell et...

Product Description: MMP13 (matrix metalloproteinase-13), also known as collagenase-3, plays a critical role in the pathogenesis of osteoarthritis (OA) by degrading type II collagen in articular cartilage. MMP13 is the primary MMP involved in cartilage destruction and is an attractive target for OA treatment....

Product Description: MMP13 (matrix metalloproteinase-13), also known as collagenase-3, plays a critical role in the pathogenesis of osteoarthritis (OA) by degrading type II collagen in articular cartilage. MMP13 is the primary MMP involved in cartilage destruction and is an attractive target for OA treatment....

Product Description: MMP13 (matrix metalloproteinase-13), also known as collagenase-3, plays a critical role in the pathogenesis of osteoarthritis (OA) by degrading type II collagen in articular cartilage. MMP13 is the primary MMP involved in cartilage destruction and is an attractive target for OA treatment....

Product Description: MMP13 (matrix metalloproteinase-13), also known as collagenase-3, plays a critical role in the pathogenesis of osteoarthritis (OA) by degrading type II collagen in articular cartilage. MMP13 is the primary MMP involved in cartilage destruction and is an attractive target for OA treatment....

Product Description: MMP13 (matrix metalloproteinase-13), also known as collagenase-3, plays a critical role in the pathogenesis of osteoarthritis (OA) by degrading type II collagen in articular cartilage. MMP13 is the primary MMP involved in cartilage destruction and is an attractive target for OA treatment....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MMP13. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MMP13. Next,...

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as...

Protein function: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV,...

Protein function: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV,...

MMP-13 Inhibitor is a pyrimidine dicarboxamide that inhibits matrix metalloproteinase-13 (MMP-13, also known as collagenase-3) with an IC50 value of 8 nM. MMP-13 Inhibitor binds to pockets that are unique to MMP-13, rather than the catalytic zinc, and thus is specific for MMP-13 over other MMPs. MMP-13 Inhibitor...

The Fluorogenic MMP13 Assay Kit is designed to measure MMP13 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.