(B-cell Lymphoma/Leukemia 2) ELISA Kit

ELISA Type: Sandwich. Detection Range: 0.16-10µg/mL. Sensitivity: 0.1µg/mL. Sample Types: Serum, plasma and other biological fluids. Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. May attenuate inflammation by impairing NLRP1- inflammasome activation, hence CASP1 activation and IL1B release. [The UniProt Consortium]