KRAS Isoform B Coupled Nucleotide Exchange (TR-FRET) Assay Kit

KRAS Isoform B Coupled Nucleotide Exchange (TR-FRET) Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82716 384 rxns - -

3 - 15 business days*

1,708.00€
 
The KRAS Isoform B Coupled Nucleotide Exchange TR-FRET Assay Kit is a TR-FRET (Time-Resolved... more
Product information "KRAS Isoform B Coupled Nucleotide Exchange (TR-FRET) Assay Kit"
The KRAS Isoform B Coupled Nucleotide Exchange TR-FRET Assay Kit is a TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) assay kit designed for screening and profiling of KRAS Isoform B antagonists/inhibitors. It monitors the binding of an effector protein such as the Ras binding domain of RAF1, (RBD-cRaf) to KRAS. The KRAS Isoform B Coupled Nucleotide Exchange TR-FRET Assay Kit comes in a convenient 384-well format, with enough purified recombinant GDP-loaded KRAS Isoform B, GTP, exchange factor SOS1 (son of sevenless homolog 1) (amino acids 564-1049), an effector protein RBD-cRAF (amino acids 50-140), assay buffer and additives for 400 reactions.
Keywords: GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, KRAS, KRAS2, RASK2,
Supplier: BPS Bioscience
Supplier-Nr: 82716

Properties

Application: Small molecule inhibitor/antagonist screening, HTS
Format: Homog.

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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