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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| BPS-82512 | 96 rxns | - | - |
3 - 8 business days* |
1,831.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The BLM Helicase Activity Assay Kit is a fluorogenic assay designed for screening and profiling... more
Product information "BLM Helicase Activity Assay Kit"
The BLM Helicase Activity Assay Kit is a fluorogenic assay designed for screening and profiling of BLM (Bloom syndrome protein) antagonists/inhibitors by monitoring their inhibitory effects on BLM-catalyzed DNA unwinding. The BLM Helicase Activity Assay Kit comes in a convenient 96-well format, with enough purified recombinant BLM (amino acids 630-1300), ATP, DNA substrate, assay buffer, and additives for 100 reactions. The DNA substrate is conjugated on one strand with the TAMRA (tetramethylrhodamine) fluorophore, and on the other strand with BHQ (Black Hole Quencher) which effectively quenches TAMRA fluorescence due to their proximity within the DNA double strand. BLM unwinding of the DNA probe separates the two strands, releasing TAMRA fluorescence. BLM activity, therefore, results in a proportional increase in fluorescence.
| Keywords: | BLM, RECQ2, RecQ2, RecQ protein-like 3, Bloom syndrome protein, DNA 3'-5' helicase BLM, RecQ-like DNA helicase BLM, DNA helicase, RecQ-like type 2, |
| Supplier: | BPS Bioscience |
| Supplier-Nr: | 82512 |
Properties
| Application: | Small molecule inhibitor/antagonist screening/titration, HTS, compound counterscreening |
| Species reactivity: | human |
| Format: | Homog. |
Database Information
| KEGG ID : | K10901 | Matching products |
| UniProt ID : | P54132 | Matching products |
| Gene ID : | GeneID 641 | Matching products |
Handling & Safety
| Storage: | -80°C |
| Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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