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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-KAB-0497.1 | 1 set (50µl & 100µg) | - | - |
10 - 15 business days* |
607.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent... more
Product information "Human Bcl-2 Antibody Pair Set"
Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells (PubMed:1508712, PubMed:8183370). Regulates cell death by controlling the mitochondrial membrane permeability (PubMed:11368354). Appears to function in a feedback loop system with caspases (PubMed:11368354). Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (PubMed:11368354). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function (PubMed:18570871, PubMed:20889974, PubMed:21358617). May attenuate inflammation by impairing NLRP1- inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). [The UniProt Consortium]
| Keywords: | BCL2, Apoptosis regulator Bcl-2, Human Bcl-2 Antibody Pair Set |
| Supplier: | Elabscience |
| Supplier-Nr: | E-KAB-0497 |
Properties
| Application: | ELISA |
| Conjugate: | No |
| Species reactivity: | human |
Database Information
| KEGG ID : | K02161 | Matching products |
| UniProt ID : | P10415 | Matching products |
| Gene ID : | GeneID 596 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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