Products from Pacific Coast Bio
Pacific Coast Biologics specializes in producing animal-free growth factor proteins and cytokines for laboratory tests and pharmaceutical development. By employing state-of-the-art technologies, they offer an extensive range of high-purity cytokines, chemokines and growth factors, and excel in providing custom E. coli fermentation and recombinant protein services, beside expert consulting in protein purification and formulation, ensuring customized solutions for your scientific requirements.
More information at: www.pacificcoastbio.com
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NT-3 (human), animal-free recombinant
Item number: PC-AF-H-NT3-100UG
Product Description: NT-3, a neurotrophic factor, shares structural kinship with beta-NGF, BDNF, and NT-4, all part of the cysteine-knot family of growth factors known for their stable dimeric structures. It's predominantly expressed by neurons in the central nervous system and activates signaling pathways through...
| Keywords: | NT-3, NTF3, HDNF, NGF-2, Neurotrophin-3, Neurotrophic factor, Nerve growth factor 2, Animal-Free Recombinant Human NT-3... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 27.2 kD |
From 132.00€
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NT-4 (human), animal-free recombinant
Item number: PC-AF-H-NT4-100UG
Product Description: NT-4 is a neurotrophic factor sharing structural similarities with beta-NGF, BDNF, and NT-3, all part of the cysteine-knot family of growth factors characterized by stable dimeric structures. It is expressed in various tissues such as the prostate, thymus, placenta, and skeletal muscle. NT-4 can...
| Keywords: | NTF4, NTF5, NT-4, NT-5, Neurotrophin-4, Neurotrophin-5, Neutrophic factor 4, Animal-Free Recombinant Human NT-4 (500 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 28.1 kD |
From 134.00€
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Oncostatin M (209 a.a.) (human), animal free recombinant
Item number: PC-AF-H-OSM209-100UG
Oncostatin M (OSM) is a multifunctional growth and differentiation factor involved in regulating neurogenesis, osteogenesis, and hematopoiesis. It is produced by activated T cells, monocytes, and Kaposi's sarcoma cells, exerting both stimulatory and inhibitory effects on cell proliferation. OSM stimulates the growth...
| Keywords: | OSM, Oncostatin-M, Animal Free Recombinant Human Oncostatin M (209 a.a.) (500 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 23.6 kD |
From 106.00€
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PDGF-AA (human), animal-free recombinant
Item number: PC-AF-H-PDGF-AA-10UG
Product Description: PDGFs exist as disulfide-linked dimers comprising two polypeptide chains, PDGF-A and PDGF-B, each weighing between 12.0 and 13.5 kDa. Among the three naturally occurring PDGFs-PDGF-AA, PDGF-BB, and PDGF-AB-all are potent mitogens affecting various cell types, including smooth muscle cells,...
| Keywords: | PDGF1, PDGFA, PDGF-1, PDGF subunit A, Platelet-derived growth factor A chain, Platelet-derived growth factor subunit A,... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 28.5 kD |
From 112.00€
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PDGF-BB (human), animal free recombinant
Item number: PC-AF-H-PDGF-BB-10UG
Product Description: PDGFs are dimers linked by disulfide bonds, composed of two 12.0-13.5 kDa polypeptide chains known as PDGF-A and PDGF-B. Among the three naturally occurring PDGFs (PDGF-AA, PDGF-BB, and PDGF-AB), they act as potent mitogens for various cell types such as smooth muscle cells, connective tissue...
| Keywords: | PDGF2, PDGFB, PDGF-2, Becaplermin, PDGF subunit B, Proto-oncogene c-Sis, Platelet-derived growth factor B chain,... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 24.3 kD |
From 107.00€
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SCF (human), animal-free recombinant
Item number: PC-AF-H-SCF-100UG
Product Description: SCF, a hematopoietic growth factor, functions by activating the c-Kit receptor. This interaction is crucial for the survival, proliferation, and differentiation of hematopoietic cells committed to melanocyte and germ cell lineages. Interestingly, Human SCF has limited activity on murine cells,...
| Keywords: | MGF, KITLG, Animal-Free Recombinant Human SCF (100 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18.4 kD |
From 64.00€
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TGF-beta 3 (human), animal-free recombinant
Item number: PC-AF-H-TGF-B3-100UG
Product Description: The three mammalian isoforms of TGF-beta, namely TGF-beta1, beta2, and beta3, activate the same receptor and provoke similar biological responses. These versatile cytokines oversee cell proliferation, growth, differentiation, and motility, along with orchestrating the synthesis and placement of...
| Keywords: | TGFB3, Animal-Free Recombinant Human TGF-beta 3 (1 mg) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 25 kD |
From 141.00€
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TPO (human), animal free recombinant
Item number: PC-AF-H-TPO-100UG
Product Description: TPO, a growth factor specific to certain lineages, emerges from the liver, kidney, and skeletal muscle. Its primary function involves stimulating the proliferation and maturation of megakaryocytes while fostering an increase in circulating platelet levels in vivo. TPO transmits its signals...
| Keywords: | TPO, Thyroid peroxidase, Animal Free Recombinant Human TPO (25 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18.6 kD |
From 116.00€
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VEGF 165 (human), animal-free recombinant
Item number: PC-AF-H-VEGF165-10UG
Product Description: VEGF stands out as a potent cytokine, driving growth and angiogenesis. It fosters endothelial cell proliferation and survival, contributing significantly to angiogenesis and vascular permeability. Its expression in vascularized tissues plays a crucial role in both normal and abnormal...
| Keywords: | VPF, VEGF, VEGFA, VEGF-A, Vascular permeability factor, Vascular endothelial growth factor A, Animal-Free Recombinant... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 38.2 kD |
From 107.00€
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TPO (murine), animal free recombinant
Item number: PC-AF-M-TPO-100UG
Product Description: TPO, a lineage-specific growth factor, originates from the liver, kidney, and skeletal muscle. It triggers the growth and development of megakaryocytes, leading to higher platelet levels in the bloodstream. TPO communicates through the c-mpl receptor, playing a crucial role in platelet...
| Keywords: | ML, MGDF, Thpo, C-mpl ligand, Thrombopoietin, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and... |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 18.7 kD |
From 116.00€
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